MartinMadSickleCellDisease

Sickle Cell Disease
 * Description: Sickle Cell disease is a disorder that affects the red blood cells, which use protein called hemogtoloin to transport oxygen from the lungs to the rest of the body. Normally red blood cells are round and flexible so they can travel freely through the narrow blood vessels. **


 * Inheritance: ** **Sickle Cell disease is inherited in an autosomal recessive pattern. This means that a child will not inherit the disease unless both the parents pass down a defective copy of the gene. People who inherit one good copy of the gene and one mutated copy of the gene are carriers. They are clinically normal but can still pass the defective gene to their children.**


 * Symptoms: The disease prevents oxygen from reaching the spleen, liver, kidneys, lungs, heart or other organs begin to die. Loss of immune function, have low red blood cell count. Episodes of pain, delayed growth, strokes and jaundice. **


 * <span style="color: black; font-family: Times,serif; font-size: 12pt;">Daily Life: **


 * <span style="color: black; font-family: Times,serif; font-size: 12pt;">Diagnosis: ****<span style="color: black; font-family: Times,serif; font-size: 12pt;">Most states routinely screen newborns for sickle cell disease with a blood test, or test called Hemoglobin electrophoresis. **


 * <span style="color: black; font-family: Times,serif; font-size: 12pt;">Treatment: ****<span style="font-family: Times,serif; font-size: 12pt;"> For babies a daily dose of penicillin to prevent deadly infections. For adults, plenty of rest, drinking lots of water, and avoiding physical activity. You can also have blood transfusions and bone marrow transplants. **


 * <span style="color: black; font-family: Times,serif; font-size: 12pt;">Research: ****<span style="font-family: Times,serif; font-size: 12pt;"> There is no cure for sickle cell disease, but treatments can help relieve symptoms and treat complications. Parents can go to genetic counseling for extra pain risks. **


 * <span style="color: black; font-family: Times,serif; font-size: 12pt;">Additional Facts: ****<span style="font-family: Times,serif; font-size: 12pt;"> unlike the normal red blood cells, which can live for 120 days, sickle shaped blood cells live only 10-20 days. Sickle cell disease his mostly affected in African Americans. **


 * <span style="color: black; font-family: Times,serif; font-size: 12pt;">Punnett Square: **




 * <span style="color: black; font-family: Times,serif; font-size: 12pt;">Pedigree Chart: **



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 * <span style="color: black; font-family: Times,serif; font-size: 12pt;">Resources: **

<span style="color: blue; font-family: Arial,sans-serif; font-size: 10pt;">Pub Med Health