Stepinskim+Adenosine+Deaminase+Deficiency

__Adenosine Deaminase Deficiency __ The immune system is affected from Adenosine Deaminase Deficiency. ADA leaves the body open to infections so this disorder is very dangerous. It is caused because chromosome 20 ismutated. If you don't have the enzyme ADA that body is not able to brake down a substance called deoxyadenosine. This will build up and destroy infection-fighting immune cells called T and B Lymphocytes.
 * Description: **


 * Inheritance: **

In order for the child to receive this disease both parents need to pass the defective gene. Adenosine Deaminase Deficiency needs to be passed by both parents for the child to inherit it.

Since Adenosine Deaminase Deficiency affects the immune system people who have it get all kinds of infections. Some infections are of the respiratory system, skin, and the gastrontestinal track. Also a person may be shorter than normal because of ADA. Most babies who are born with ADA die within a few months of living.
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 * Daily Life: **

During a mother's pregnancy Adenosine Deaminase Deficiency can be found. Doctors will take some of the tissue from where the baby develops. Or they take a blood sample from the umbilical cord and look at the enzyme levels. When a baby is born doctors can take a sample of its blood to see if it contains ADA. This is the most common way to find it in a male.
 * Diagnosis: **

There is no real cure for Adenosine Deaminase Deficiency. With treatments doctors are trying to improved the immune system. > >
 * Treatment: **
 * <span style="color: black; font-family: Times,serif; font-size: 12pt;"><span style="color: black; font-family: Times,serif; font-size: 12pt;">Taking <span style="font-family: arial,helvetica,sans-serif; font-size: 13px; line-height: 19px;">healthy immune cells from a biological match.
 * <span style="color: black; font-family: Times,serif; font-size: 12pt;">Transfusions of red blood cells from a healthy donor that contains ADA.
 * <span style="color: black; font-family: Times,serif; font-size: 12pt;">Enzyme replacement therapy, involving repeated injections of the ADA enzymes.
 * <span style="color: black; font-family: Times,serif; font-size: 12pt;">Gene therapy- Insert synthetic DNA containing a normal ADA gene into immune cells

<span style="color: black; font-family: Times,serif; font-size: 12pt;">Doctors all over the world are trying to find more easy treatments for people with Adenosine Deaminase Deficiency. The treatments we have now are mostly types of transplants so doctors are looking for easier ways. Doctors are not having any luck trying to prvent this. it It is very rare so it makes it difficult to research.
 * <span style="color: black; font-family: Times,serif; font-size: 12pt;">Research: **

<span style="color: black; font-family: Times,serif; font-size: 12pt;">Adenosine Deaminase Deficiency is a very rare disease. From research doctors figured out that about 10 children are diagnosed with this disease in the U.S each year. In 1990 doctors preformed the fist successful gene therapy. It was done on a young girl with ADA deficiency named Ashanti deSilva.
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<span style="font-family: Arial,sans-serif; font-size: 10pt;">[|Http://learn.genetics.utah.edu/units/disorders/whatare]

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