beniteze+Maple+Syrup+Urine+Disease+(MSUD)

Maple Syrup Urine Disease (MSUD) Maple Syrup Urine Disease is a very deadly disease. The Disease affects the way the body breaks down the three amino acids (leucine, isoleucine, and valine). When these acids are not being made into protein they can only be recycled or broken down into and used for energy. Soon the person who has this disease with end up with to dangerously high of amino acids in there blood. This soon will cause a rapid degeneration of brain cells and death if left untreated.
 * Description: **


 * Inheritance: **

MSUD is inherited in an autosomal recessive pattern. Both parents have to have a copy of the MSUD gene for a child to get it. If both parents have the disease there is a 50% chance of the offspring being a carrier, there is a 25% chance of the child of actually getting the disease, and also a 25% of the offspring not being affected at all.

Symptoms of this disease start within weeks of birth. Some of them are loss of appetite, fussiness, and it gives your urine a very sweet smell. The urine often with smell like maple syrup and that is where its name originated. If MSUD is not treated right away the symptoms get more severe. These more severe symptoms are seizures which could lead to a coma. If the disease is still not treated after that the infant will die within the first few months of life.
 * Symptoms: **


 * Daily Life: **

media type="custom" key="9710758" width="160" height="160"


 * Diagnosis: **

In most states in the US babies are checked for MSUD when they are first born. They will usually be checked within the first 24 hours of life. Most states check for MSUD by taking a small blood sample from the heel. They do this to check the baby for high leucine levels.

The treatments for MSUD have to start right away to prevent any brain damage to the infant. The treatment involves dietary restriction. This means that the child must have special formula with very low levels of leucine, isoleucine, and valine. When the child grows up they have to stay away from high protein foods.
 * Treatment: **

There is no current research on the cure for MSUD because they already have one. They are still looking into the certain diet for a person with MSUD.
 * Research: **

Luckily only 1 180,000 babies will be born with MSUD. This means it is a very rare disease. The Mennonites in Lancaster, Pennsylvania it is a lot more common. 1 in 176 babies are born with this disease.
 * <span style="color: black; font-family: Times,serif; font-size: 12pt;">Additional Facts: **


 * <span style="color: black; font-family: Times,serif; font-size: 12pt;">Punnett Square: **




 * <span style="color: black; font-family: Times,serif; font-size: 12pt;">Pedigree Chart: **

Pictures:
 * <span style="color: black; font-family: Times,serif; font-size: 12pt;">Resources: **


 * <span style="color: black; font-family: 'Times New Roman',serif; font-size: 12pt;">Include hyperlink to websites that you used as part of your research **<span style="color: black; font-family: 'Times New Roman',serif; font-size: 10.5pt;">.

<span style="color: blue; font-family: Arial,sans-serif; font-size: 10pt;">Pub Med Health