fischerc+Colon+Cancer

Colon Cancer Colon cancer occurs when cell growth stops and cells divide out of control. This forms a tumor. If this occurs within the colon, it is called colon cancer. The colon is located in the lower body; it is the first part of the lower intestine. Colon cancer is caused by the gene mutations FAP or HNPCC. It is inherited from parents or relatives. Colon cancer affects the stomach and bowels. Symptoms include diarrhea, blood in the stool, vomiting, bloating, cramps and weight loss.
 * Description: **


 * Inheritance: **

FAP and HNPCC gene mutations are inherited in an autosomal dominant pattern. If one parent possesses one of these genes, there is a 5O% chance of the next generation having one of these gene mutations. The gene APC is a tumor suppressor. If a person inherits one bad copy of APC, they are nearly guaranteed to obtain colon cancer by age 4O. In a likewise way, if the gene HNPCC is inherited, an 8O% chance of getting colon cancer is developed. This gene disorder also increases chances of other types of cancer, such as ovarian, stomach, brain, and liver.

The symptoms of colon cancer are diarrhea, blood in the stool, vomiting, bloating, cramps, and weight loss.
 * Symptoms: **


 * Daily Life: **

media type="custom" key="9659484"


 * Diagnosis: **

A doctor can screen a patient for colon cancer by checking for blood in the patient’s feces. They can also use a thin flexible tube called a simidoscope to check for polyps. A silvery-white chemical called barium can also be inserted up the patient’s rectum. This is shown on an x-ray screen. Another way is to do a colonoscopy, where a colonoscope is used to compose a biopsy of the colon, and pieces of tissue are removed and checked for growths. The last way is by a DNa-based stool test. A sample is taken to look for genetic defects associated with colon cancer.

Colon cancer is extremely treatable. About 9O% of patients survive after treatment. It can be treated using chemotherapy or radiation that kills all cells that divide too rapidly. Also, surgery could occur to remove cancers and polyps.
 * Treatment: **

Scientists are learning more about colon cancer. They are learning more about the changes in DNa that cause colon cancer. Also, Chemoprevention is the use of natural or man-made chemicals to lower a person’s risk of getting cancer. People who take folic acid, vitamin D supplements, or calcium have a lower risk of colorectal cancer. A diet high in fruits and vegetables can also help reduce risk.
 * Research: **

“People with FAP can develop hundreds and even thousands of polyps in their colon, while people with HNPCC develop relatively few.”
 * Additional Facts: **

<span style="color: black; font-family: Times,serif; font-size: 12pt;"> “Colorectal cancer is the secon leading cause of cancer-related death in the US.” <span style="color: black; font-family: Times,serif; font-size: 12pt;">“Colorectal cancer screening is recommended for men and women beginning at age 5O.” <span style="color: black; font-family: Times,serif; font-size: 12pt;"> - //cdc.gov//


 * <span style="color: black; font-family: Times,serif; font-size: 12pt;">Punnett Square: **




 * <span style="color: black; font-family: Times,serif; font-size: 12pt;">Pedigree Chart: **




 * Pictures:**


 * <span style="color: black; font-family: Times,serif; font-size: 12pt;">Resources:[[image:CDR0000415499.jpg width="320" height="296" align="left"]] **

<span style="color: black; font-family: 'Times New Roman',serif; font-size: 12pt;">

<span style="color: black; font-family: 'Times New Roman',serif; font-size: 12pt;">

<span style="font-family: 'Times New Roman',serif;"> [] [] []

<span style="color: blue; font-family: Arial,sans-serif; font-size: 10pt;">Pub Med Health