julianos+Sickle+cell+disease

Sickle Cell
 * Description: Sickle Cell Disease affects the red blood cells, which use a protein called hemoglobin to transport oxygen from the lungs to the rest of the body. Patients with Sickle Cell Disease have a mutation in a gene on chromosomes that code for beta subunit of the hemoglobin protein. **


 * Inheritance: In a autosomal recessive pattern. This means the child will not inherit the disease unless both parents pass down a defective copy of the gene. People who inherit one good copy of the gene and one mutated copy are carriers. They are clinically normal but can still pass the defective gene to their children. **


 * Symptoms: Sickle cell disease prevents oxygen from reaching the speech and etc. Without oxygen the cells that make up these organs will begin to die. That includes: strokes, jaundice, and yellowish skin. **

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 * Diagnosis: Most states usually test newborns for Sickle Cell disease with a simple blood test. If the disorder is not detected at birth, a blood sample can be taken. The test will determine whether a person has Sickle Cell Disease, or whether he/she is a carrier of hemoglobin gene. **


 * Treatment: A way is rehydrating the patient with plenty of fluids and giving oxygen when necessary. It is also possible to exchange transfusions so that abnormal Sickle Cells are replaced by normal blood. **


 * Research: They are trying to prevent this disorder by preventing this by genetic counseling and by testing the blood of potential parents for the abnormal Sickle cell trait. Another way is to use amniocentesis. **


 * Additional Facts: This disease commonly affects African Americans about 1 out of every 500 African American babies have sickle sell anemia. This disease is more common for people in Africa, India, the Caribbean, the Middle East, and the Mediterranean. Sickle cell disease can cause recurring chills and fever. **


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 * Resources: Book **


 * Author: David B. Jacoby **
 * <span style="color: black; font-family: 'Times New Roman',serif; font-size: 12pt;">Title: Encyclopedia of family health **
 * <span style="color: black; font-family: 'Times New Roman',serif; font-size: 12pt;">Place of publication: Tarrytown, New York **
 * <span style="color: black; font-family: 'Times New Roman',serif; font-size: 12pt;">Publisher: Marshall Cavendish **
 * <span style="color: black; font-family: 'Times New Roman',serif; font-size: 12pt;">Pages used: 1734-1739 **
 * <span style="color: black; font-family: 'Times New Roman',serif; font-size: 12pt;">Date of publication: 1998 **

<span style="font-family: Times,serif; font-size: 16pt;">Internet:
 * Website title: http://learngenetics.utah.edu.units/disorders/whataregd/ **
 * Web article: Sickle Cell anemia **
 * Date of website: January 24, 2011 **
 * Date information recived: May 19, 2011 **